Effect of exercise on left ventricular mechanical efficiency in conscious dogs.

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Effect of exercise on left ventricular mechanical efficiency in conscious dogs.

BACKGROUND We studied the effect of exercise (7.2 to 8.0 km/h) on the efficiency of the conversion of metabolic energy to external work or stroke work (SW) by the left ventricle (LV). METHODS AND RESULTS Energy use was calculated from LV myocardial oxygen consumption per beat (MVO2). LV volume was calculated from orthogonal dimensions and coronary flow measured with ultrasonic flow probes. Th...

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Mechanical Efficiency in Conscious Dogs

Background We studied the effect of exercise (7.2 to 8.0 km/h) on the efficiency of the conversion of metabolic energy to external work or stroke work (SW) by the left ventricle (LV). Methods and Results Energy use was calculated from LV myocardial oxygen consumption per beat (MVo2). LV volume was calculated from orthogonal dimensions and coronary flow measured with ultrasonic flow probes. The ...

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Effect of the ouabain-quinidine interaction on left ventricular and left atrial function in conscious dogs.

The effect of the ouabain-quinidine interaction was examined in 10 conscious dogs. Left ventricular (LV) pressure, LV dP/dt, LV diameter and left atrial (LA) diameter were measured with high-fidelity micromanometers and sonomicrometer crystals. Ouabain, 0.025 mg/kg, significantly (p less than 0.05) increased LV dP/dt, LV and LA fractional shortening and LV and LA velocity of circumferential fib...

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Influence of the force-frequency relation on left ventricular function during exercise in conscious dogs.

BACKGROUND The magnitude of the force-frequency effect on myocardial contractility in the conscious animal has been studied at rest, but it has not been assessed during exercise. METHODS AND RESULTS The influence of heart rate (HR) changes were evaluated during treadmill exercise in eight preinstrumented, conscious dogs in which high-fidelity left ventricular (LV) pressure, LV volume (by sono...

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Effect of Supine Exercise on Left Ventricular

RESPONSE to physical exercise in man has been studied extensively. For any given workload, a predictable change in blood pressure, heart rate, and cardiac output has been shown to occur. Rushmerl has pointed out that the response of stroke volume to exercise, however, may be variable both in experimental animals and in man. He has also demonstrated that not only the amount, but also the directi...

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ژورنال

عنوان ژورنال: Circulation

سال: 1994

ISSN: 0009-7322,1524-4539

DOI: 10.1161/01.cir.90.6.3047